In a major step to fight climate change, the Biden administration is raising vehicle mileage standards to significantly reduce emissions of planet-warming greenhouse gases, reversing a Trump-era rollback that loosened fuel efficiency standards.

A final rule issued Monday would raise mileage standards starting in the 2023 model year, reaching a projected industry-wide target of 40 miles per gallon by 2026. The new standard is 25% higher than a rule finalized by the Trump administration last year and 5% higher than a proposal by the Environmental Protection Agency in August.

“We are setting robust and rigorous standards that will aggressively reduce the pollution that is harming people and our planet – and save families money at the same time,” EPA Administrator Michael Regan said. He called the rule “a giant step forward” in delivering on President Joe Biden’s climate agenda “while paving the way toward an all-electric, zero-emissions transportation future.″

The move comes a day after Democratic Sen. Joe Manchin delivered a potentially fatal blow to Biden’s $2 trillion social and environmental policy bill, jeopardizing Democrats’ agenda and infuriating the White House. The West Virginia senator said he could not support the sweeping bill, which includes a host of climate proposals, saying it was too expensive and could spark inflation and expand the growing federal debt.

The now-stalled bill includes a $7,500 tax credit to buyers to lower the cost of electric vehicles.

The administration will “continue to fight tirelessly” for the EV tax credits and other incentives in the so-called Build Back Better bill, Regan said, but even without them, “we believe that we proposed a rule that is doable, it’s affordable, it’s achievable, and we’re excited about it.”

The new mileage rules are the most ambitious tailpipe pollution standards ever set for passenger cars and light trucks. The standards raise mileage goals set by the Trump administration that would achieve only 32 miles per gallon in 2026. Biden had set a goal of 38 miles per gallon in August.

The standards also will help expand the market share of zero emissions vehicles, the administration said, with a goal of battery electric and plug-in hybrid vehicles reaching 17% of new vehicles sold in 2026. EVs and plug-in hybrids are expected to have about 7% market share in 2023.

The EPA said the rule would not only slow climate change, but also improve public health by reducing air pollution and lower costs for drivers through improved fuel efficiency.

Biden has set a goal of cutting U.S. greenhouse gas emissions by at least half by 2030 as he pushes a history-making shift in the U.S. from internal combustion engines to battery-powered vehicles.

He has urged that components needed to make that sweeping change — from batteries to semiconductors — be made in the United States, too, aiming for both industry and union support for the environmental effort, with the promise of new jobs and billions in federal electric vehicle investments.

While ambitious, the new standards provide adequate lead time for auto manufacturers to comply at reasonable costs, the administration said. EPA’s analysis shows the industry can comply with the final standards with modest increases in the numbers of electric vehicles entering the fleet.

Environmental and public health groups mostly hailed the new rules, while the trade association representing most major automakers reacted cautiously.

Automakers are “committed to achieving a cleaner, safer, and smarter future,” but EPA’s final rule for greenhouse gas emissions is more aggressive than originally proposed, “requiring a substantial increase in electric vehicle sales, well above the 4% of all light-duty sales today,” said John Bozzella, president and CEO of the Alliance for Automotive Innovation. The group represents manufacturers producing nearly 99% of new cars and light trucks sold in the U.S.

“Achieving the goals of this final rule will undoubtedly require enactment of supportive governmental policies – including consumer incentives … and support for U.S. manufacturing and supply chain development,” Bozella said in a statement.

“We can all breathe a collective sigh of relief now that a strong federal clean car rule is restored,” said Morgan Folger of Environment America, an advocacy group.

Despite pushback from the auto industry, the rule will significantly reduce air and climate pollution, Folger said. She called the announcement “a win” on climate that will help create “an onramp to a future with zero emissions from our cars and trucks.”

EPA’s action is “an important step forward that will reduce greenhouse gases and air pollution and improve lung health,” added Harold Wimmer, president and CEO of the American Lung Association.

EPA called the new rule critical to address climate change. Transportation is the single largest source of greenhouse gas emissions in the United States, making up 29% of all emissions. Within the transportation sector, passenger cars and trucks are the largest contributor, accounting for 58% of all transportation-related emissions and 17% of overall U.S. carbon emissions.

The final standards will contribute toward a goal set by the 2015 Paris climate agreement to keep the increase in the global average temperature to well below 2° Celsius above pre-industrial levels, the EPA said. The U.S. rejoined the Paris agreement on Biden’s first day in office after former President Donald Trump had withdrawn the U.S. from the global pact.

The new rules would begin with the 2023 car model year and increase emissions reductions year by year through model year 2026. The rule accelerates the rate of emissions reductions to between 5 and 10% each year from 2023 through 2026, the EPA said, far higher than under previous rules.