Beloved New York eatery Shake Shack is planting its buns on the West Coast for the first time, opening Tuesday on a busy block in West Hollywood.

But in picking Southern California for its westward expansion, Shake Shack may be facing its biggest challenge yet: whether a Big Apple burger joint can survive in the birthplace of America’s burger culture.

This is the place, after all, where McDonald’s opened its first restaurant. The Southland is the locus of the cult of In-N-Out. Many gourmet burger purveyors — the Habit, the Counter and Umami Burger, among them — earned their greasy stripes here.

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