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A chemical described as a skin and eye irritant was spilled Monday and resulted in the closure of the north and south lanes of North Glassell Street in Orange, authorities said.

A call was received about 12:25 p.m. about a “hazardous release” or spill from a truck, which carried the chemical Isocyanate, that was stopped in a parking lot, said Ian MacDonald of the City of Orange Fire Department.

The spill was described as a “limited amount of liquid” and part of the truck’s cargo, MacDonald stated.

Isocyanate is a skin and eye irritant that is reactive with water and flammable, MacDonald said.

North Glassell Street was closed between Meats and Grove Avenue, the City of Orange Police Department said in a Twitter message.

Streets near the leak were closed and nearby businesses were also told to close their doors and windows but no one was evacuated, MacDonald said.

There has been no injuries to civilians or firefighters, MacDonald said, and the material was isolated and expected to be picked-up shortly.

Twenty-five firefighters were on scene, MacDonald said.

The spill and road closure was reported at 1:03 p.m. on the City of Orange Police Department’s Twitter account. The closure was expected to last two hours, officials stated at the time.

About 30 minutes later, authorities said to use alternative routes until further notice in another Tweet.

The roads were expected to be open by 6:30 p.m. after a city-hired private contractor prepared the road for cleaning, said Orange police Lt. Fred Lopez.

At 8:35 p.m., both north and south lanes of North Glassell Street were open, the City of Orange Police Department’s Twitter account stated.

Officials said earlier there was “no known threat to public safety” from the spill.

https://twitter.com/CityOfOrangePD/status/1018956265559490560

KTLA’s Steve Bien and Matt Phillips contributed to this story.