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A motorist traveling in the wrong direction died along with another driver in a fiery collision on the 110 Freeway in the Harbor Gateway area early Saturday, officials said.

The California Highway Patrol received calls about a vehicle heading south on the northbound lanes around 4:12 a.m., Officer Andrew Minor said.

The first caller reported spotting a wrong-way driver in the El Segundo area, according to CHP.

Responding officers later found an overturned vehicle and a second car engulfed in flames about 4 to 5 miles away, on the overpass near the 182nd Street onramp, Minor said.

The crash left the vehicles, a sedan and an SUV, badly damaged, and it’s unclear which was traveling the wrong direction, Minor said.

It remains under investigation whether speed, drugs or alcohol were involved in the crash, according to the officer.

CHP issued a SigAlert, closing down the northbound lanes as officers assessed the scene. It was canceled at around 9:15 a.m.