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A wrong-way car and a Greyhound bus collided Sunday morning on a highway in eastern Indiana, killing the car’s driver and sending 20 people to hospitals, officials said.

The crash happened about 7 a.m. Sunday on Interstate 70 near the Ohio border, about 70 miles east of Indianapolis.

The bus had a driver and 23 passengers on board, all of whom were sent to hospitals, a Greyhound spokeswoman told the Los Angeles Times. She said two of the passengers were admitted to Reid Hospital in Richmond while others were treated for minor injuries and released, and that the driver was airlifted to Methodist Hospital in Indianapolis.