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What to do if someone overdoses on an opioid, such as fentanyl

Joe Solomon, co-director of Charleston-based Solutions Oriented Addiction Response, holds a dose of the opioid overdose reversal drug Narcan at the Unitarian Universalist Congregation of Charleston in Charleston, W.Va., on Sept. 6, 2022. (Leah Willingham/Associated Press)

The California Overdose Surveillance Board shows there were an estimated 5,722 fentanyl-related overdose deaths in 2021 in the state.

In Sacramento County, the data shows an estimated 119 people lost their lives in 2021 due to fentanyl poisoning, and Sacramento County says 50 have died from the same cause in the first seven months of 2022.


The dashboard for San Francisco County shows there were an estimated 382 fentanyl-related deaths in 2021, 101 in San Joaquin County and 1,361 in Los Angeles County.

The California Department of Public Health said fentanyl-related overdose deaths for younger people, between the ages of 10 and 19, have also greatly increased from 2018 to 2020. Overdose deaths involving fentanyl for those ages in 2018 was 36, and it was 261 in 2020.

Overall, there were 107,622 fatal overdoses nationwide in 2021, according to the CDC.

The risk of street drugs, such as cocaine and pills, having fentanyl is high, Sacramento County health officials say, and people may unknowingly consume fentanyl, which could lead to an overdose.

According to the CDPH, the Drug Enforcement Administration said it found two out of every five counterfeit pills had a potentially lethal dose of fentanyl.

Below are the steps on what to do and what not to do when someone overdoses on fentanyl or another opioid, according to the CDC.

How to spot an overdose

What to do when someone overdoses

California has a 911 “Good Samaritan law” that provides protection for those seeking help. To learn more about the law, click or tap here

If there are doubts as to whether the person overdosed on an opioid, it should still be used. 

“Naloxone won’t harm someone if they’re overdosing on drugs other than opioids, so it’s always best to use it if you think someone is overdosing,” the CDC said.

A second dose of naloxone can be used if there is no reaction to the first dose. 

“More than one dose of naloxone may be required when stronger opioids like fentanyl are involved,” the CDC said.

What not to do when someone overdoses

“If you cannot wake the person by shouting, rubbing your knuckles on the sternum (center of the chest or rib cage), or light pinching, the person may be unconscious,” the Substance Abuse and Mental Health Services Administration advised.

It could cause them to go into shock. They could slip or drown if left unattended.

They could choke on or inhale the vomit, which could be fatal.

If you or someone you know is struggling with addiction to alcohol or drugs, the Department of Health Services offers support and treatment services.